TRIM29 (Lung Squamous Cell Carcinoma Marker) MBS438997 from MyBioSource.com

Product Specs
ItemTRIM29 (Lung Squamous Cell Carcinoma Marker)
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS438997
Quantity0.1 mg
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
ConcentrationPurified Ab with BSA and Azide at 200ug/ml
Conjugate/TagUnconjugated
Format200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
ReactivityHuman
TargetTRIM29
IsotypeIgG2a kappa
Molecular WeightAntigen: 66kDa
CloneTRIM29/1041
HostMouse
ImmunogenIt recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies
NCBI Full Gene Nametripartite motif containing 29
NCBI Gene AliasesATDC
ClonalityMonoclonal